An antagonist should not be administered in the absence of clinically significant respiratory or cardiovascular depression. Drug information for the health care professional.
You can also ask your child's health care provider or a pharmacist. If the patient vomits within 1 hour of administration, the NAC dose should be repeated. Nonopiate-containing analgesic fixed combinations: Antiemetics, 5-HT 3 receptor antagonists e. Nonopiate component may limit dosage of opiate component.
For relief of mild to moderate pain. Adrenal insufficiency reported in patients receiving opiate agonists or opiate partial agonists.
Rockville, MD; Aug Allergic reactions may occur but are rare. FDA's strongest warning, called a Contraindication, to the drug labels of codeine and tramadol alerting that codeine should not be used to treat pain or cough and tramadol should not be used to treat pain in children younger than 12 years. Potential for drug to impair mental alertness or physical coordination; use caution when driving or operating machinery until effects on individual are known.
Regardless of the quantity ingested, and particularly if it is estimated to be 7. Philadelphia, PA; Apr. FDA News August 17, Large overdoses of acetaminophen are potentially fatal, unless an appropriate antidote such as N-acetylcysteine NAC is administered early after drug ingestion, usually within 12 to 16 hours.
Performance of activities requiring mental alertness and physical coordination may be impaired. Head Injury and Increased Intracranial Pressure: Katz N, Mazer NA. Pharmacogenetics and adverse drug reactions. Use with caution; reduce dosage of codeine c.
Patients using this drug should be cautioned accordingly. Onset occurs in 15—30 minutes. The respiratory depressant effects of narcotics and their capacity to elevate cerebrospinal fluid pressure may be markedly exaggerated in the presence of head injury or intracranial lesions or pre-existing increase in intracranial pressure.
After 24 hours, earlier symptoms tend to abate and the patient may even feel well for one or a few days.