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This article has been cited by other articles in PMC. In the event that any of your registration information changes in the future, you will promptly update your registration information on the Site. Anatomy and physiology of the uterine cervix. Cervical Ripening and Induction of Labor With a Viable Fetus Compared with placebo, misoprostol causes cervical ripening before induction with oxytocin.

Nonpharmacologic Cervical Ripening

Second trimester pregnancy termination: It has been shown that misoprostol increases myometrial contraction as well as decreases cervical resistance 12. Buccal or sublingual misoprostol for cervical ripening and induction of labour.

My doctor has prescribed Cytotec misoprostol for me to take the night before. Clin Obstet Gynecol ; Buccal misoprostol offers the effectiveness and decreased side effects of vaginal administration combined with high acceptability for both patient and staff.

Am J Obstet Gynecol. Access to Services features may require an active paid subscription account "Subscription". The study was blinded doubly till the final outcome.

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Preoperative application of vaginal misoprostol decreased the need of further cervical dilatation in large number of cases. Rectally administered misoprostol for the treatment of postpartum hemorrhage unresponsive to oxytocin and ergometrine: According to the most current studies, the rate varies from 9.

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A randomized trial of the effect of moistening misoprostol before vaginal administration when used with methotrexate for abortion.

Acta Obstet Gynecol Scand. Bring gel to room temperature before application, per manufacturer's instructions. Preutthipan S, Herabutya Y.

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The present study showed a positive balance between the benefits and risks of the use of misoprostol; however, it is not feasible to conclude that its use is imperative prior to IUD insertion in nulligravidas and IUD insertion should not be canceled when the medication is unavailable.

Applications to women's reproductive health care. J Obstet Gynaecol Res. There is also evidence that the addition of mg of mifepristone to the induction protocol decreases the interval to delivery for termination of pregnancy.

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Comparison of prostaglandin E 1 misoprostol with prostaglandin E 2 dinoprostone for labor induction. Does an acidic medium enhance the efficacy of vaginal misoprostol for pre-abortion cervical priming? The ideal dosing regimen for second-trimester procedures is unknown.