Disulfiram drug classification

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Disulfiram pronounced as dye sul' fi ram. Before using this medication, tell your doctor or pharmacist your medical history, especially of: If you need an identification card, ask your pharmacist or doctor how to get one.

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Do not store in the bathroom. Disulfiram blocks the oxidation of alcohol at the acetaldehyde stage during alcohol metabolism following disulfiram intake causing an accumulation of acetaldehyde in the blood producing highly unpleasant symptoms. What would you like to print?

The serum concentration of Disulfiram can be decreased when it is combined with St. It is important for you to keep a written list of all of the prescription and nonprescription over-the-counter medicines you are taking, as well as any products such as vitamins, minerals, or other dietary supplements.

Wear a medical alert tag or carry an ID card stating that you take Antabuse. Check the label to see if any food or medicine product contains alcohol. In a small number of patients, a transient mild drowsiness, fatigability, impotenceheadache, acneform eruptions, allergic dermatitisor a metallic or garlic -like aftertaste may be experienced during the first two weeks of therapy.

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The maximum recommended daily dose is milligrams. Although disulfiram remained the most common pharmaceutical treatment of alcohol abuse till the end of the 20th century, today it is often replaced or accompanied with newer drugs, primarily the combination of naltrexone and acamprosatewhich directly attempt to address physiological processes in the brain associated with alcohol abuse.


Who should not take Disulfiram? Pharmacology Mechanism of Action Produces sensitivity to EtOH via blocking its oxidation at acetaldehyde stage, resulting in unpleasant reactions including palpitations, hypotension, chest pain, nausea, vertigo, thirst, flushing, and nausea. Cautions When EtOH ingested by patient taking disulfiram: Patients should clearly understand consequences of disulfiram therapy and give informed consent before use.

Disulfiram Dixanthogen Mesulfen Thiram.

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Increases risk of ataxia, unsteady gait, or marked behavioral changes. If it is near the time of the next dose, skip themissed dose and resume your usual dosing schedule. Most commonly, these are "non-preferred" brand drugs or specialty prescription products. After alcohol intake under the influence of disulfiram, the concentration of acetaldehyde in the blood may be five to 10 times higher than that found during metabolism of the same amount of alcohol alone.


Women's Health Subscribe to the Women's Health newsletter for the latest on disease prevention, fitness, sex, diet, anti-aging, and more from WebMD. Disulfiram alone in the rat's diet did not lead to such tumors.

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Catechin Meciadanol Naringenin Tritoqualine. Views Read Edit View history.