Codeine in pregnancy bnf

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Codeine should not be used in children below the age of 12 years because of the risk of opioid toxicity due to the variable and unpredictable metabolism of codeine to morphine see section 4.

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The risk-benefit of continued use should be assessed regularly by the prescriber. Patient Platform Limited has used all reasonable care in compiling the information but make no warranty as to its accuracy.

If this continues to be a problem, speak with your doctor.

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Liver damage is possible in adults who have taken 10g or more of paracetamol. Management Immediate treatment is essential in the management of paracetamol overdose. The anticoagulant effect of warfarin and other coumarins may be enhanced by prolonged regular use of paracetamol with increased risk of bleeding; occasional doses have no significant effect.

The most common side-effects are feeling sick, constipation, feeling sleepy, and dry mouth. Please check that this is the correct company before contacting them. If you have any questions about this medicine ask your pharmacist.

The information below lists reported adverse reactions, ranked using the following frequency classification:. Along with their useful effects, most medicines can cause unwanted side-effects although not everyone experiences them. The table below contains some of the most common ones associated with codeine. Opioid analgesics may depress neonatal respiration and cause withdrawal effects in neonates of dependent mothers.

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Assess your symptoms online with our free symptom checker. One tablet every 6 hours when necessary to a maximum of 4 tablets in 24 hours.

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You will find a full list in the manufacturer's information leaflet supplied with your medicine. Acute renal failure with acute tubular necrosis, strongly suggested by loin pain, haematuria and proteinuria may develop even in the absence of severe liver damage.

Before taking codeine

The pupils may be pin-point in size; nausea and vomiting are common. Abnormalities of glucose metabolism and metabolic acidosis may occur. Treatment with N-acetylcysteine may be used up to 24 hours after ingestion of paracetamol, however, the maximum protective effect is obtained up to 8 hours post-ingestion. Symptoms Central nervous system depression, including respiratory depression, may develop but is unlikely to be severe unless other sedative agents have been co-ingested, including alcohol, or the overdose is very large.

About codeine

The operation that you have selected will move away from the current results page, your download options will not persist. Codeine is indicated in patients older than 12 years of age for the treatment of acute moderate pain which is not considered to be relieved by other analgesics such as paracetamol or ibuprofen alone. Do not keep out-of-date or unwanted medicines. Management of patients who present serious hepatic dysfunction beyond 24h from ingestion should be discussed with the NPIS or a liver unit.

Do not drink alcohol Dry mouth, sweating, tummy pain may be caused by spasm of the bile ducts Speak with your doctor if troublesome.

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