Erythromycin as motility agent
We are indebted to our colleague Paul McAndrew for his encouragements, his valuable suggestions and for critically reviewing the manuscript. The emergence of Streptococcus pneumoniae resistant to macrolide antimicrobial agents: Only one randomized placebo-controlled trial has been conducted.
Better navigate the business aspects of medicine and stay on top of the changing healthcare landscape. Effects of enteral and parenteral nutrition on gut mucosal permeability in the critically ill.
Improvement of gastric emptying in diabetic gastroparesis by erythromycin. Supplemental Content Full text links. Hyperglycemia attenuates the gastrokinetic effect of erythromycin and affects the perception of postprandial hunger in normal subjects. Summary of the antimicrobial action of erythromycin. Therefore it may become a useful therapeutic alternative to other prokinetic agents in critical illness.
Failure of a motilin receptor agonist ABT to relieve the symptoms of functional dyspepsia in patients with and without delayed gastric emptying: They have been used for a wide variety of conditions such as gastro-oesophageal reflux, chronic constipation, post-surgical intestinal dysmotility, and for facilitating the passage of naso-enteric tubes. Molecular detection of the macrolide efflux gene: BTS guidelines for the management of community acquired pneumonia in adults.
However, it is recognized that the number and sample sizes of clinical trials in this area are small and that finer details such as the ideal doses of the drugs are yet to be established.
However, the anaerobic gut flora has been shown to participate in the exchange and accumulation of genetic elements encoding for erythromycin A resistance. Disease and Condition Articles.
Receive exclusive offers and updates from Oxford Academic. Anaphylaxis is uncommon with all macrolide antibiotics and the incidence is in the range of one per million patients treated with erythromycin.
Increased expression of Qnr is sufficient to confer clinical resistance to ciprofloxacin in Escherichia coli. The ideal dosing of erythromycin still requires clarification; the above regimen produced satisfactory outcomes, but similar results might have been achieved with twice daily dosing [ 20 ].
Next article in issue: The erythromycin resistance gene from the Bacteroides conjugal transposon Tc r Em r is nearly identical to erm G from Bacillus sphaericus.
Not a Medscape Member? They include different antibiotics exerting different selective powers 23 and local spread of resistant or susceptible clones, in addition to those factors influencing antibiotic consumption, e.