Therapeutic class of pantoprazole

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No dosage adjustment is necessary in patients with renal impairment or in patients undergoing hemodialysis.

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Do not stop taking pantoprazole without first checking with your doctor, or unless told to do so by your doctor. For adult patients who are CYP2C19 poor metabolizers, no dosage adjustment is needed. Due to its effects on gastric acid secretion, pantoprazole can reduce the absorption of drugs where gastric pH is an important determinant of their bioavailability.

May potentiate saquinavir, digoxin, methotrexate consider temporary withdrawal of the PPI ; monitor.


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Food may delay absorption up to 2 hours; the extent of absorption is not affected. Swallow the mixture of applesauce or apple juice and medication right away within 10 minutes without chewing or crushing the granules.

Learn the health benefits of yogurt. Co-administration of atazanavir or nelfinavir with proton pump inhibitors is expected to substantially decrease atazanavir or nelfinavir plasma concentrations and may result in a loss of therapeutic effect and development of drug resistance.

Effectiveness for EE has not been demonstrated in patients less than 1 year of age.

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Browse Drugs and Medicines. The serum concentration of Technetium Tcm sestamibi can be increased when it is combined with Pantoprazole. Read about what causes ulcers, heartburn, The total clearance also increased with increasing age only in children under 3 years of age.

Also, the number of doses you take each day, the time allowed between doses, and the length of time you take the medicine depend on the medical problem for which you are using the medicine. Headache, diarrhea, nausea, abdominal pain, vomiting, flatulence, dizziness, arthralgia; possible C.

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Acid Reflux Differences and Similarities Heartburn and acid reflux are not the same thing. If you become pregnant while taking pantoprazole, call your doctor. Read and follow these instructions carefully. Pantoprazole is a substituted benzimidazole indicated for the short-term treatment up to 16 weeks in the healing and symptomatic relief of erosive esophagitis.

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Warning Signs of Type 2 Diabetes. Pantoprazole can cause an increase in the absorption of Methylphenidate resulting in an increased serum concentration and potentially a worsening of adverse effects. Acute interstitial nephritis may occur at any point during PPI therapy and is generally attributed to an idiopathic hypersensitivity reaction.

Reproduction studies have been performed in rats at oral doses up to 88 times the recommended human dose and in rabbits at oral doses up to 16 times the recommended human dose and have revealed no evidence of impaired fertility or harm to the fetus due to pantoprazole.