Calcitonin and alendronate together
However, more women receiving a tablet i. Apps At Your Fingertips. This study was, therefore, designed to compare directly the effects of intranasal calcitonin and alendronate on BMD and bone turnover when used for treatment of osteoporosis in postmenopausal women.
Calcitonin has demonstrated the ability to reduce vertebral fracture rates with minimal changes in bone density. Many women, however, are unwilling to take estrogen due to concerns about breast cancer or unwanted side effects 1. To evaluate a longer duration of therapy, the study is being extended to assess the effects of alendronate and calcitonin over 24 months. How to cite this comment: It is important to stay with the plan on which you and your healthcare provider have agreed.
The patients receiving calcitonin were instructed to switch to a new bottle every 2 weeks. Many people have trouble taking their medicines. Learn how you can live better. Some physicians have reported that calcitonin may decrease bone pain associated with osteoporotic fractures.
Stay Connected Join our community to learn more about osteoporosis, or connect with others near you who are suffering from the disease. A history of a gastrointestinal disorder other than an esophageal motility disorder or use of a nonsteroidal anti-inflammatory agent was not a reason for exclusion. In daily practice, alendronate enhanced significantly BMD both in lumbar spine and femoral neck. There are two categories of osteoporosis medications: Patients with a BMD more than 4 sd below the young normal mean at either the PA lumbar spine or femoral neck, a prevalent vertebral fracture on lateral thoracic or lumbar spine radiographs, or a history of minimal trauma hip fracture were excluded due to the use of a placebo in this study.
When given to patients with osteoporosis, calcitonin produces modest increases in bone mass. Ethics committee approval was obtained for all study sites. It may be hard to remember what each medicine is for, and how and when you should take each one. Always consult your doctor about your medical conditions. Previous article in issue: You are here Conditions Osteoporosis Osteoporosis Medications. Follow-up bone densitometry was not made available to patients or study personnel with the exception of the DXA operator.
The effectiveness of Calcitonin tends to plateau approximately 18 years after menopause. Although the increases in BMD reported with alendronate, in general, are greater than those reported with calcitonin, a direct comparison is necessary to adequately understand the relative efficacy of these two therapies.
Analyses were conducted on all reported AEs.
Medicines Approved to Prevent and/or Treat Osteoporosis
Tests comparing the treatment groups were declared significant at the 0. It furthers the University's objective of excellence in research, scholarship, and education by publishing worldwide. Generate a file for use with external citation management software.