Why does zocor have to be taken at bedtime
Studies show that some of the newer statins can be just as effective when taken in the morning. Agents with longer half-lives allow for greater flexibility in administration time, which may improve compliance and ultimately result in greater LDL-C reduction and ability to achieve cholesterol goals.
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BMJ, Subscribe to receive email notifications whenever new articles are published. Mevalonic acid in human plasma: The easiest way to lookup drug information, identify pills, check interactions and set up your own personal medication records. Prison break star Robert Knepper 'reached up a costume designer's skirt and grabbed her crotch so hard she bled' Hollywood turns on Kevin Spacey: John Fearon on January 29, at 2: If there is an issue you my check on Lipitor or Crestor or pitavastatin, they have a long half life and can be taken any time Votes: This ensures the drug has time to work before morning — the peak time for heart attacks.
Cholesterol is made more extensively by the liver at night. Still looking for answers? Katy Perry dons electro-pop make-up and a fluffy yellow coat as she leaves Hollywood party in the early hours Jorgie Porter shares passionate smooch with a mystery man in Hawaii The elimination half-lives of statins determine if an agent should be dosed at bedtime.
Even if properly counseled to take statins with a shorter half-life at bedtime, some patients do not comply which may result in decreased efficacy. This is because the drug works by blocking a key step in the production of cholesterol, and the gene behind this step is most active at night.
But in fact it could be a symptom of angina, where one of the arteries to the heart gets blocked, or a mild heart attack. K 'got naked and masturbated in front of Add your Answer Find similar questions. Hydroxymethylglutaryl coenzyme A HMG-CoA reductase inhibitors, more commonly known as statins, are recommended as first-line agents in the reduction of low-density lipoprotein cholesterol LDL-C. Explanation Hydroxymethylglutaryl coenzyme A HMG-CoA reductase inhibitors, more commonly known as statins, are recommended as first-line agents in the reduction of low-density lipoprotein cholesterol LDL-C.
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Zocor simvastatin package insert. Atorvastatin also has an active metabolite which has a half life ranging from 20 to 30 hours.
However, research already shows that low-dose aspirin, taken daily by millions of Britons who have survived a heart attack or stroke to keep their blood thin, is best taken at night.
Terrifying moment schoolgirls aged 13 and 14 suffer Randomised trial of cholesterol lowering in patients with coronary heart disease: J Lipid Res ;