Simvastatin evening administration

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Always ask if your statin should be taken with food or at a specific time of day.

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However, the extended-release version of lovastatin, Altoprev, should be taken at bedtime. Pooled results showed no evidence of a difference in total cholesterol MD 4. Further high-quality trials with longer-term follow-up are needed to confirm the results of this review.

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Grapefruit juice can cause that statin to stay in your body much longer, and the drug can build up. Expert Perspective Follow experts from across more than 30 medical specialties who share their viewpoints and guidance on medical developments as they unfold. The effect of the timing of statin administration on hyperlipidaemia Background Cardiovascular disease CVDwhich comprises heart attacks myocardial infarctionangina, and strokes, is the principal cause of death in the world and is a major cause of morbidity worldwide.

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Develop Your Own Curriculum. The content is not directed, edited, approved, or otherwise influenced by the advertisers represented on this page, with exception of the potential recommendation of the broad topic area. Learn from Experienced Professionals. This article changed my life! Comparison between morning and evening doses of simvastatin in hyperlipidemic subjects.

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Your doctor knows your personal medical issues and is your best source for information. Get helpful advice on your cases from a community of physicians. Please try again later. Simvastatin is an example of a statin that works better if taken in the evening.

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That includes supplements, over-the-counter medications, and prescription drugs. See a certified medical professional for diagnosis.

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Serious risks include damage to your muscles, kidneys, and liver. None of the studies included were judged to be at low risk of bias. High LDL cholesterol is associated with an increased risk of coronary artery disease.

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Find this article online at Journal of Clinical Lipidology.