Calcipotriene betamethasone dipropionate
Calcipotriene and Betamethasone Ointment Dosage and Administration
Apply once daily, or as directed by physician. Avoid tanning booths and sunlamps. There are no adequate and well-controlled studies in pregnant women.
Another study from van de Kerkhof assessed the impact of treatment with the two-compound ointment on patient quality of life QoL. Use of more than one corticosteroid-containing product at the same time may increase the total systemic corticosteroid exposure. Drug Dev Ind Pharm. Minor There is evidence that calcipotriene can be absorbed in amounts that are sufficient to produce systemic effects, including elevated serum calcium; hypercalcemia has been observed in normal prescription use.
However, animal studies demonstrated that calcipotriene is — times less potent than calcitriol on calcium metabolism when given systemically. Comparision of studies on the treatment of psoriasis vulgaris with two-compound ointment. Recovery of HPA axis function is generally prompt and complete upon discontinuation of the topical corticosteroid.
The foam formulation has been studied in two pivotal, randomized, double-blind trials in patients with mild to severe plaque psoriasis.
How to use Calcipotriene-Betamethasone DP Ointment Read the Patient Information Leaflet provided by your pharmacist before you start using this product and each time you get a refill. It may take a week to see any improvement and 4 weeks to see the full benefit of this medication. Calcipotriene did not elicit any genotoxic effects in the Ames mutagenicity assay, the mouse lymphoma TK locus assay, the human lymphocyte chromosome aberration test, or the mouse micronucleus test.
A novel aerosol foam formulation of calcipotriene 0. Consult your pharmacist or local waste disposal company. If someone has overdosed and has serious symptoms such as passing out or trouble breathingcall Views Read Edit View history. Psoriasis is a multifactorial process associated with immunologic dysregulation.
Instruct mothers to avoid application to the breast while breast-feeding. US residents can call their local poison control center at Instruct patients not to bandage, cover, or wrap the treated area. Do not bandage, wrap, or cover the treated area unless your doctor instructs you to do so.
Ask your doctor for details. MC is the major metabolite in plasma.